OBJETIVO: medir a frequência fundamental de 122 crianças de seis a oito anos de idade, meninos e meninas, sem alterações vocais, avaliadas por meio da escala Rasat. MÉTODOS: a análise perceptivo-auditiva foi realizada através da escala RASAT e para a análise acústica computadorizada foi utilizado o programa de software Vox Metria, analisando-se a média da frequência fundamental de amostras da vogal [ε] sustentada. Participaram deste estudo 122 crianças, 58 meninos e 64 meninas com idade variando de seis a oito anos e 11 meses de idade do ensino fundamental, da Rede Municipal de Niterói-RJ, nascidos e residentes na cidade, pré-selecionadas através de um protocolo de triagem. RESULTADOS: os resultados obtidos neste estudo foram: frequência fundamental média de 239,60 Hz para as meninas e 237,17 Hz para os meninos, obtendo-se uma média geral de 238,44 Hz. CONCLUSÃO: conclui-se que os achados permitiram a comparação com resultados de pesquisas realizadas anteriormente, contribuindo com novos dados para a padronização da frequência fundamental das vozes infantis brasileiras.

To examine changes in body mass index (BMI) among older Brazilian adults and associated factors. Longitudinal, population-based study, conducted in São Paulo, Brazil. Adults aged 60 years or over (n = 1,796) from the first wave of data collection from the Health, Well-Being, and Aging Study (SABE Project) conducted from 2000 to 2010. Repeated mixed-effects linear regression was used to analyze longitudinal changes in BMI and to examine whether sociodemographic characteristics, health conditions, and social behaviors were associated with these changes. Mean BMI decreased after 70 years. Men had lower BMI than women (β = -1.86, 95%CI: -2.35; -1.37). Older adults who consumed alcohol (β = 0.30, 95%CI: 0.06; 0.54), had more than one chronic disease (β = 0.19, 95%CI: 0.26; 0.72) and who did not perform physical activity (β = 0.56, 95%CI: 0.38; 0.74) had higher BMI. Subjects who smoked (β = -0.40, 95%CI: -0.76; -0.04) and who reported having eaten less food in recent months (β = -0.48, 95%CI: -0.71; -0.24) had lower BMI. In older Brazilians, several sociodemographic characteristics, health conditions, and behaviors predict BMI. Increasing prevalence of chronic diseases and growing sedentary behaviors in Brazil may have detrimental effects on BMI at older ages.

Introduction: Digital Health is a field of knowledge and practice focused on the use of innovative technologies to enhance healthcare services. At the São Paulo State Department of Health, Digital Health is among the top priorities in health initiatives; however, there remains a need to strengthen knowledge to support the digital transformation of the Brazilian Unified Health System (SUS). Objective: To assess the conditions for evaluation through an evaluability study of the Digital Health Program in the Telehealth models applied in Primary Health Care, Specialty Outpatient Clinics, Intensive Care Units, and Correctional Facilities, developed by the São Paulo State Department of Health and integrated into the São Paulo State Health Plan 2024–2027. Methodology: Evaluability study conducted in the following stages: document analysis; stakeholder mapping; development of a logic model; formulation of evaluative questions; and construction of a measurement matrix comprising specific criteria, indicators, and parameters. Data were obtained from sources such as the Brazilian Ministry of Health’s “Digital Health Strategy for Brazil 2020–2028,” the São Paulo State Health Plan 2024–2027, and the Work Plan of the Digital Health Innovation Program of the São Paulo State Department of Health. Results: The study developed a Measurement Matrix composed of 20 indicators, which will support the identification of strengths and weaknesses in the implementation of the Digital Health Program. Conclusions: The findings of the study indicate the feasibility, utility, and practicability of evaluating the Digital Health Program within the São Paulo State Department of Health.

RESUMO Objetivo analisar a internalização do cuidado com o corpo pelo escolar com a doença falciforme com base na teoria do desenvolvimento de Vigotski e no conceito de cuidado de Collière. Método Estudo qualitativo com 15 escolares que convivem com a doença falciforme, acompanhados em ambulatório na cidade de Vitoria – ES. A técnica utilizada foi a entrevista individual e a análise temática. A hidratação corporal, o brincar, a prevenção e manejo da crise falcêmica, a alimentação e as roupas foram as unidades temáticas que emergiram. Resultados Os participantes referiram ingerir variados tipos de líquidos. As brincadeiras foram predominantemente ativas. Os medicamentos foram de reparação e manutenção da saúde. Não se evidenciou consumo de alimentos saudáveis. Observou-se a utilização de roupas adequadas ao frio. A dor foi um signo da internalização do cuidado e do conhecimento para brincadeiras. A diminuição de líquidos e roupas inadequadas desencadearam a crise falcêmica. Considerações Finais Evidenciaram-se a internalização do conhecimento e dos cuidados mediados pela dor e o despreparo dos professores pela falta de conhecimento. Implicações para a prática este estudo poderá subsidiar a melhor articulação entre profissional de saúde, criança e escola.

O teste do olhinho é um exame que consiste na identificação de um reflexo vermelho vindo da retina, que aparece quando se ilumina o olho do bebê. O fenômeno é semelhante ao observado nas fotografias. Esse teste pode detectar qualquer alteração que cause obstrução à passagem da luz no eixo visual, cuja identificação precoce pode possibilitar o tratamento no tempo certo e o desenvolvimento normal da visão.  A prevalência de cegueira entre as crianças é cerca de 10 vezes menor do que entre os adultos, porém a cegueira infantil continua a ser uma alta prioridade por causa do número de anos a serem vividos as cegas, e devido ao fato de que cerca da metade dos estimados 1,4 milhões de casos de cegueira em crianças com menos 15 anos de idade poderiam ter sido evitados. Assim sendo, o estudo desses testes no presente trabalho visa uma análise da ocorrência dessas patologias na região. Trata-se de um estudo epidemiológico transversal e quantitativo à partir da análise de prontuários médicos feitos pela clínica São Lucas, que atende planos de sáude, SUS e particular. O resultado não foi parecido com a literatura mundial, concluindo que, existem particularidades nesse teste quando feito por oftalmologista.

Previous results showed the ethyl acetate phase (SP-AcOEt), obtained from aerial parts of Solanum paludosum, relaxed the aorta isolated in the endothelium-dependent and -independent manner. The vasorelaxant effects of SP-AcOEt was not characterized on aorta rings endothelium-denuded, thus this work aimed to elucidate the mechanisms endothelium-independent vasorelaxation on rat isolated aorta. The aorta was isolated from Wistar rats and mounted in glass baths containing 6 mL of normal Krebs physiological solution with pH at 7.4. The preparation was maintained at 37ºC and bubbled continuously with a mixture of 95% O2 and 5% CO2. Aortic rings were maintained for 1 hour by a resting tension of 1g and next were contracted with phenylephrine after the sustained contraction ACh was added to access the integrity of the endothelium. SP-AcOEt relaxed pre-contracted aorta by KCl-30mM or -80mM in a similar manner, suggesting blockade CaV, but not channel-K+ participating. SP-AcOEt also inhibited the contraction induced by CaCl2 and relaxed pre-contracted aorta by (±)-BayK8644 (EC50 = 16.9±1.3 μg/mL), which confirms the involvement of L-type CaV blockade. SP-AcOEt presented vasorelaxation endothelium-independent that involves L-type CaV blockade.

Abstract Background: The increased incidence of cardiovascular disease in women occurs during the climacteric period, especially after menopause. Objective: The aim of this study was to identify risk factors among climacteric women with and without coronary artery disease (CAD). Method: This cross-sectional study was performed in the Catheterization Laboratory at the Federal University Hospital of Maranhão, in the Northeast region of Brazil, between March 2012 and July 2013. We included 31 climacteric women who went to the care center for cardiac catheterization. They were divided into groups after catheterization results: Group I (with DAC) and Group II (without CAD). Statistical analysis: Categorical variables were described by means of frequencies and percentages, numerical variables by mean ± standard deviation or median (Quartile.3 - Quartile.1); the Shapiro-Wilk test was used to verify the normality of quantitative data. Fisher's exact test was used for categorical data comparisons. For continuous data, we used Student's test or the Mann-Whitney for unpaired samples; statistical significance was set at p < 0.05. Results: We evaluated groups with CAD (n = 13) and without CAD (n = 18). The results showed a mean age between the groups of 57.92 ± 5.15 and 51.72 ± 4.63 years, respectively. Among the cardiovascular risk factors, the most prevalent among women with CAD were menopause (84.62%), systemic arterial hypertension (SAH) (69.23%) and sedentary life style (69.23%). Conclusion: We concluded that, in addition to menopause itself, SAH and sedentary lifestyle were the most prevalent cardiovascular risk factors among women with CAD.