Contamination of ground water as a consequence of soil leaching processes is an issue of major concern. In this context, a simulation of the soil leaching process was designed. A sequential injection (SI) method to monitor the soil leaching of iron complexes with in-line rain simulation for leachate production is described. The developed methodology comprises the SI determination of both iron(III) and 3-hydroxy-4-pyridinones iron(III) complexes, coupled to a mini soil column (mSC) for displaying in-line rain simulations. The described SI method enabled iron(III) determination within the range 2.0–35 μmol L−1, with a detection limit of 0.42 μmol L−1, and determination of iron(III) complexes in the range 1.0–45 μmol L−1. It was successfully applied to leachates from laboratory scale soil columns (LSSC), with good precision for both iron(III) and iron complexes determinations: calculated relative standard deviation (RSD) of 5% and 6%, respectively. A step further in automation and miniaturization was attained with the incorporation of a mini soil column for the in-line leachate production. The system enabled the soil leachate production and assessment in less than 5 min, including determinations in triplicate.

Anemia in chronic kidney disease is a major complication is multifactorial and may be present even in the early stages of renal failure. This work aims to develop a bibliometric analysis to assess the national and international scientific production of anemia in chronic kidney disease. We conducted a bibliometric study using the database “Scopus” and the terms “anemia” and “chronic kidney disease”, and the results obtained in stratified tables for comparison using the number of publications of the major contributors to the total publications . The study showed that Brazil produced only 1.5% of the total publications, although showing an upward trend in the number of publications, while the United States produced 28.8% of the total publications, also recording an increase in the number of publications . It was found also that the areas of the main journals with publications on renal anemia were hematology and nephrology.

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