Magnetic Resonance Imaging (MRI) is a non-invasive tool for the clinical assessment of low-prevalence neuromuscular disorders. Automated diagnosis methods might reduce the need for biopsies and provide valuable information on disease follow-up. In this paper, three methods are proposed to classify target muscles in Collagen VI-related myopathy cases, based on their degree of involvement, notably a Convolutional Neural Network, a Fully Connected Network to classify texture features, and a hybrid method combining the two feature sets. The proposed methods were evaluated on axial T1-weighted Turbo Spin-Echo MRI from 26 subjects, including Ullrich Congenital Muscular Dystrophy and Bethlem Myopathy patients at different evolution stages. The hybrid model achieved the best cross-validation results, with a global accuracy of 93.8%, and F-scores of 0.99, 0.82, and 0.95, for healthy, mild and moderate/severe cases, respectively.

Magnetic Resonance Imaging (MRI) is a non-invasive tool for the clinical assessment of low-prevalence neuromuscular disorders. Automated diagnosis methods might reduce the need for biopsies and provide valuable information on disease follow-up. In this paper, three methods are proposed to classify target muscles in Collagen VI-related myopathy cases, based on their degree of involvement, notably a Convolutional Neural Network, a Fully Connected Network to classify texture features, and a hybrid method combining the two feature sets. The proposed methods were evaluated on axial T1-weighted Turbo Spin-Echo MRI from 26 subjects, including Ullrich Congenital Muscular Dystrophy and Bethlem Myopathy patients at different evolution stages. The hybrid model achieved the best cross-validation results, with a global accuracy of 93.8%, and F-scores of 0.99, 0.82, and 0.95, for healthy, mild and moderate/severe cases, respectively.

Muscle texture may be used as a descriptive feature for the segmentation of skeletal muscle in Magnetic Resonance Images (MRI). However, MRI acquisition is not always ideal and the texture richness might become compromised. Moreover, the research for the development of texture quality metrics, and particularly no-reference metrics, to be applied to the specific context of MRI is still in a very early stage. In this paper, a case study is established from a texture-based segmentation approach for skeletal muscle, which was tested in a thigh Dixon MRI database. Upon the obtained performance measures, the relation between objective image quality and the texture MRI richness is explored, considering a set of state-of-the-art no-reference image quality metrics. A discussion on the effectiveness of existing quality assessment methods in measuring MRI texture quality is carried out, based on Pearson and Spearman correlation outcomes.

Medical professionals are viewing an increasing number of images and videos in their clinical routine. However, various types of distortions can affect medical imaging data, and therefore impact the viewers’ experienced quality and their clinical practice. Thus it is necessary to quantify this impact and understand how the viewers, i.e., medical experts, perceive the quality of (distorted) images and videos. In this paper, we present an up-to-date review of the methodologies used in the literature for the subjective quality assessment of medical images and videos and discuss their merits and drawbacks depending on the use case.

Muscle texture analysis in Magnetic Resonance Imaging (MRI) has revealed a good correlation with typical histological changes resulting from neuromuscular disorders. In this research, we assess the effectiveness of several features in describing intramuscular texture alterations in cases of Collagen VI-related myopathy. A T1-weighted Turbo Spin-Echo MRI dataset was used (N_subj = 26), consisting of thigh scans from subjects diagnosed with Ullrich Congenital Muscular Dystrophy or Bethlem Myopathy, with different severity levels, as well as healthy subjects. A total of 355 texture features were studied, including attributes derived from the Gray-Level Co-occurrence Matrix, the Run-Length Matrix, Wavelet and Gabor filters. The extracted features were ranked using the Support Vector Machine Recursive Feature Elimination (SVM-RFE) algorithm with Correlation Bias Reduction, prior to cross-validated classification with a Gaussian kernel SVM.