The presence of new technologies inside vehicles is becoming more common. Due to this fact, the potential changes produced on the driving task and also on the road safety must be examined. With the intention of contributing to amplify this knowledge, the present research aimed to study the impact of multiple visual and auditory inputs from in-vehicle information systems on the driver behaviour. It was investigated the interaction with more than one invehicle system (a guidance system and a mobile phone device) and verified its consequences on the drivers’ activity. To accomplish this goal two experimental moments were planned: one conducted in a real context and another in a simulated environment. Results revealed that the interaction with two in-vehicle systems produced considerable changes on drivers’behaviour once subjects assumed more frequently unsafe actions like: inadequate indication of their actions; abrupt and unexpected adoption of determined behaviours; and also negligence of some road information from the environment. It was also verified that this situation produced more severe consequences to the driving task performance of elderly drivers. The management of all sources of information induced them to compromise their safety and be more frequently involved in dangerous situations.