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  1. 1

    The impact of methylene blue in colon cancer: a retrospective multicentric study

    Publication
    by Carvalho, A
    Other Authors: Limbert, M; Cabral, F; Fareleira, A; Duarte, A; Barroca, R et al.
    Introduction: Discussions about the optimal lymph node (LN) count and its therapeutic consequences have persisted over time. The final LN count in colorectal tissues is affected by a variety of variables (patient, tumor, operation, pathologist, immune response). Methylene blue (MB) intra-arterial injection is a simple and inexpensive procedure that can be used to enhance lymph node count. Aim: Analyze whether there is a statistically significant difference between intra-arterial methylene blue injection and conventional dissection for the quantification of lymph nodes and determine if there is a variation in the quality of lymph node acquisition. Methods and results: Between 2015 and 2022, we conducted a retrospective analysis of colon cancer specimens. Data on the tumor's features, the number of lymph nodes, the number of lymph nodes that were positive, and other factors had been collected. The number of identified lymph nodes was highly significantly improved in the study group (P < 0.05). There is not a significant statistical difference between groups regarding the metastatic lymph node harvest. The group with injection of intra-arterial methylene blue shows a significantly decreased (P < 0.05) of the of cases with less than 12 lymph nodes recovered comparing with the control group. Conclusion: Colon cancer specimens can be easily evaluated concerning lymph nodes using the methylene blue method. Therefore, we strongly advise this approach as a standard procedure in the histological evaluation of colon cancer specimens in order to maximize the identification of lymph nodes. However, the detection of metastatic lymph nodes was unaffected significantly.
    2024 article Portugal open access
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  3. 3

    Isolated fracture of the coracoid’s process base 9-years after a Latarjet procedure: A novel case report

    Publication
    by Rocha Carvalho, D
    Other Authors: Claro, R
    Abstract: Coracoid fractures (CF) are relatively uncommon injuries and in most cases are associated with other concomitant lesions to the superior shoulder suspensory complex (SSSC). As far to the authors’ knowledge, there are no reports of an isolated acute fracture of the base of the coracoid process, years after Latarjet procedure. The authors present the case of a 51-year-old male and non-professional cyclist, with a history of left shoulder Latarjet procedure 9-years ago, sustained a high energy trauma to the left anterior shoulder. Imaging studies revealed a non-displaced fracture to the base of the reminiscent of the coracoid’s process, without other associated injuries to the SSSC or to the coracoid’s graft. A conservative treatment was approached. 1-year after CF, the patient is asymptomatic with CT scan confirming healing of the fracture in an adequate position. Despite very rare, fracture of the reminiscent of coracoid process should always be ruled out after a direct high energy trauma to the anterior shoulder, in patients with previous Latarjet procedure.
    2023 article Portugal open access
  4. 4

    Catheter-associated urinary tract infection in medical patients of a Portuguese hospital: incidence and risk factors

    Publication
    by Lobão, MJ
    Other Authors: Taborda, AL; Grilo, A; Sepúlveda, C; Taborda, F; Castro, J et al.
    2019 conference output Portugal open access
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  6. 6

    Obesity- attributable costs of absenteeism among working adults in Portugal

    Publication
    by Destri, K
    Other Authors: Alves, J; Gregório, MJ; Dias, SS; Henriques, AR; Mendonça, N et al.
    Background: Obesity leads to poor health outcomes and may adversely affect work productivity. This study, aimed to investigate the obesity- attributable costs of absenteeism among working adults in Portugal. Methods: The study population included individuals actively working at baseline from the Epidemiology of Chronic Diseases Cohort (EpiDoC), a large Portuguese population-based prospective study. Body mass index was measured at baseline and in two follow-up interviews. Absenteeism in each wave of the EpiDoC was assessed by the question "Did you have a sick leave in the previous 12 months? yes/no", followed by "How many days did you miss work due to sickness in the previous twelve months?". Body mass index (BMI) was classified into underweight, normal weight, overweight, and obese, based on the standard World Health Organization definition. Association between obesity and absenteeism was estimated with the negative binomial regression model adjusted for BMI, chronic diseases, and lifestyle. Obesity- attributable costs were calculated using lost gross income during the time absent from work, through the human-capital approach. Results: The EpiDoC included 4338 working adults at baseline. Of these, 15.2% were obese at the beginning of the study and 22.7% of the population had been absent from work in the last 12 months. Participants with obesity missed 66% more days at work (IRR: 1.66; CI 95%:1.13-2.44; (p = 0.009.) than those with normal weight. The odds of having been absent from work were 1.4 times higher in obese compared to non-obese individuals (CI 95%: 1.18-1.67; p < 0.01) adjusted to sex and type of work. Obese individuals missed 3.8 more days per year than those with normal weight (95%CI: 3.1-4.5). Extrapolating to the entire Portuguese working population, absenteeism due to obesity incurred an additional cost of €238 million per year. Conclusion: Obesity imposes a financial burden due to absenteeism in Portugal. Employers and national health regulators should seek effective ways to reduce these costs.
    2022 article Portugal open access
  7. 7

    Value of Surgery and Nonsurgical Approaches for Cervical Spondylotic Myelopathy: WFNS Spine Committee Recommendations

    Publication
    by Parthiban, J
    Other Authors: Alves, OL; Chandrachari, KP; Ramani, P; Zileli, M
    OBJECTIVE: Cervical spondylotic myelopathy (CSM) has become a prevalent cause of spinal cord dysfunction among the aging population worldwide. Although great strides have been made in spine surgery in past decades, the optimal timing and surgical strategy to treat CSM have remained controversial. In this article the authors aimed to analyze the current trends in studies of CSM and to summarize the recent advances of surgical techniques in its treatment. METHODS: The PubMed database was searched using the keywords pertaining to CSM in human studies that were published between 1975 and 2018. Analyses of both the bibliometrics and contents, including the types of papers, authors, affiliations and countries, number of patients, and the surgical approaches were conducted. A systematic review of the literature was also performed with emphasis on the diagnosis and treatment of mild CSM. RESULTS: A total of 1008 papers published during the span of 44 years were analyzed. These CSM studies mainly focused on the natural history, diagnosis, and treatment, and only a few prospective randomized trials were reported. For the authors and affiliations, there was a shift of clustering of papers toward Asian countries in the past decades. Regarding the treatment for CSM, there was an exponential growth of surgical series published, and there was a trend toward slightly more anterior than posterior approaches through the past decade. Patients with CSM had increased risks of neurological deterioration or spinal cord injury with nonoperative management. Because surgery might reduce the risks, and early surgery was likely to be correlated with better outcomes, there was a trend toward attention to mildly symptomatic CSM. CONCLUSIONS: There is emerging enthusiasm for research on CSM worldwide, with more publications originating in Asian countries over the past few decades. The surgical management of CSM is evolving continuously toward early and anterior approaches. More prospective investigations on the optimal timing and choices of surgery are therefore needed.
    2019 article Portugal open access
  8. 8

    Peripherally Inserted Central Catheter Placement in a Cardiology Ward: A Focus Group Study of Nurses’ Perspectives

    Publication
    by Salgueiro-Oliveira, A
    Other Authors: Bernardes, RA.; Adriano, D; Serambeque, B; Santos-Costa, P; Sousa, LB. et al.
    2021 article Portugal open access
  9. 9

    Surgical treatment of an all-spine epidural empyema

    Publication
    by Reinas, R
    Other Authors: Alves, ÓL; Kitumba, D; Baptista, AM
    Spinal epidural empyema (SEE) is a severe infectious disease of the spine which may cause significant morbidity and mortality. Surgical drainage of the empyema is a key feature. However, approach-related morbidity may be significant in very extensive collections. We present the case of a 55-year-old female with an empyema due to methicillin-susceptible Staphylococcus aureus spawning from C2 to S1. She underwent drainage of the pus through skip-level laminectomies and catheter epidural saline irrigation. The technique described was both safe and effective at treating the SEE, and the patient returned to normal life.
    2023 article Portugal open access
  10. 10

    History of Spinal Neurosurgery and Spine Societies

    Publication
    by Zileli, M
    Other Authors: Sharif, S; Fornari, M; Ramani, P; Jian, F; Fessler, R et al.
    2020 article Portugal open access